Scientific evidence
- The beneficial effect of AmF/SnF2 on oral malodour has been demonstrated in several studies. Marked reductions in aerobic and anaerobic bacterial counts were observed in healthy subjects (Quirynen et al. 2002a). Using the mouthrinse twice daily for 7 days also resulted in an improvement in oral malodour. Comparable results were obtained with a 0.2% chlorhexidine mouthrinse in this study.
- Other randomised, controlled studies support the efficacy of SnF2 in reducing oral malodour (Farrell et al. 2007, Gerlach et al. 1998). In a study with 384 subjects, organoleptic scores and VSC levels were significantly (p<0.01) lower after 5 days with a dentifrice containing 0.45% SnF2 than with those containing 0.24% NaF (Gerlach et al. 1998).
- The anti-VSC activity of Sn2+ ions has been shown to correlate with the high affinity of Sn2+ for sulphide ions (Young et al. 2001). An in vitro study showed that both insoluble stannous pyrophosphate and its corresponding soluble salt inhibited VSC formation in saliva by 99-100% (Jonski et al. 2004).
